Dutch Connectome Lab

The dutch connectome lab is a group of neuroscience enthusiasts with all kinds of backgrounds (biology, physics, math, medicine, artificial intelligence) working at the Complex Trait Genetics Lab and the center for neurogenomics and cognitive research, part of the Neurocience Campus Amsterdam, VU Amsterdam and Amsterdam UMC.

Our focus: Integrative brain function depends on efficient functional communication within a massive web of billions to trillions of neuronal connections. All this is happening within what we call our 'brain'. Our research focus is to get a better understanding of the wiring architecture of the brain's network and to understand how abnormal connectivity may lead to neurological and psychiatric brain diseases. One of our recent pets is to map the communication hubs of the brain, examining how they 'rich club' together, at what price and, in particular, why... to keep our 1.5 kg of brain mush together?

Watch our research movie


These are the people of the Dutch Connetome Lab.


Recently published papers

  • Cross-sectional and longitudinal assessment of the upper cervical spinal cord in motor neuron disease
    van der Burgh HK, Westeneng H, Meier JM, van Es MA, Veldink JH, Hendrikse J, van den Heuvel MP, van den Berg LH | NeuroImage: Clinical | 16-08-2019
  • Shared vulnerability for connectome alterations across psychiatric and neurological brain disorders
    de Lange SC, Scholtens LH, van den Berg LH, Boks MP, Bozzali M, Cahn W, Dannlowski U, Durston S, Geuze E, van Haren NEM, Hillegers MHJ, Koch K, Angeles Jurado M, Mancini M, Marques-Iturria I, Meinert S, Ophoff RA, Reess TJ, Repple J, Kahn RS, van den Heuvel MP | Nature human behaviour | PDF | 05-08-2019
  • The road ahead in clinical network neuroscience
    Douw L, van Dellen E, Gouw AA, Griffa A, de Haan W, van den Heuvel MP, ..., Stam CJ | Network Neuroscience | 30-07-2019
  • Genetic mapping of cell type specificity for complex traits
    Watanabe K, Mirkov MU, de Leeuw CA, van den Heuvel MP, Posthuma D | Nature Communications | 19-07-2019
  • The human connectome from an evolutionary perspective
    Ardesch DJ, Scholtens LH, van den Heuvel MP | Progress in Brain Research | 09-07-2019

more... [ 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2005 ]

Our favorites

  • Connectome Disconnectivity and Cortical Gene Expression in Patients With Schizophrenia
    Romme IAC, de Reus MA, Ophoff RA, Kahn RS, van den Heuvel MP | Biol Psychiatry. | 27-07-2016
  • Comparative Connectomics
    van den Heuvel MP, Bullmore ET, Sporns O | Trends Cogn Sci. | 26-03-2016
  • Rich club organization supports a diverse set of functional network configurations
    Senden M, Deco G, de Reus MA, Goebel R, van den Heuvel MP | Neuroimage. | 01-08-2014
  • An anatomical substrate for integration among functional networks in human cortex
    van den Heuvel MP, Sporns O | J Neurosci. | 04-09-2013
  • Impaired cerebellar functional connectivity in schizophrenia patients and their healthy siblings
    Collin G, Hulshoff Pol HE, Haijma SV, Cahn W, Kahn RS, van den Heuvel MP | Front Psychiatry | 16-12-2011

more... [ 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2005 ]

Please let us know if you are looking for other resources or data.

Internship positions are available for highly motivated students, who are as excited as us to explore the connectome.

Lab members have wide variety of backgrounds and are working on a broad range of topics, so it is likely that there will be a project of interest for you. To give an impression, we list a few previous projects:

  • Linking connectomes from various modalities (EEG, resting state fMRI, DTI)
  • Studying different modalities of the developing brain
  • Exploring the microscopic connectome of the C. elegans
  • Relating genetics and connectomics in disorders
  • Developing new mathematical tools for network analysis
If you are interested, please contact us through the contact form on this website.

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